|
KMID : 0383820150780030190
|
|
Tuberculosis and Respiratory Diseases
2015 Volume.78 No. 3 p.190 ~ p.195
|
|
|
Predictors of Relapse in Patients with Organizing Pneumonia
|
|
Kim Min-Jung
Cha Seung-Ick
Seo Hye-Won
Shin Kyung-Min
Lim Jae-Kwang
Kim Hye-Ra
Yoo Seung-Soo
Lee Jae-Hee
Lee Shin-Yup
Kim Chang-Ho
Park Jae-Yong
|
|
|
Abstract
|
|
|
Background : Although organizing pneumonia (OP) responds well to corticosteroid therapy, relapse is common during dose reduction or follow-up. Predictors of relapse in OP patients remain to be established. The aim of the present study was to identify factors related to relapse in OP patients.
Materials and Methods : This study was retrospectively performed in a tertiary referral center. Of 66 OP patients who were improved with or without treatment, 20 (30%) experienced relapse. The clinical and radiologic parameters in the relapse patient group (n=20) were compared to that in the non-relapse group (n=46).
Results : Multivariate analysis demonstrated that percent predicted forced vital capacity (FVC), PaO2/FiO2, and serum protein level were significant predictors of relapse in OP patients (odds ratio [OR], 0.82; 95% confidence interval [CI], 0.70?0.97; p=0.018; OR, 1.02; 95% CI, 1.00?1.04; p=0.042; and OR, 0.06; 95% CI, 0.01?0.87; p=0.039, respectively).
Conclusion : This study shows that FVC, PaO2/FiO2 and serum protein level at presentation can significantly predict relapse in OP patients.
|
|
|
KEYWORD
|
|
|
Cryptogenic Organizing Pneumonia, Recurrence, Vital Capacity
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|
|